BEER-SHEVA, ISRAEL -- December 31, 2009 -- Dr. Amnon Sintov, a senior lecturer in the Department of Biomedical Engineering at Ben-Gurion University of the Negev, has received a Dekker Award from the Bachmann-Strauss Dystonia & Parkinson Foundation to further his groundbreaking research on Parkinson's disease treatment.
Dr. Sintov focuses on the potential clinical benefit provided by the transdermal delivery of L-DOPA (levodopa), a drug commonly prescribed to treat Parkinson's disease. Transdermal drug patches are a convenient method for delivering therapeutics into a patient's blood in a continuous and controlled manner.
Currently, when L-DOPA is given orally to Parkinson patients it is eliminated from the body very quickly, causing sharp and frequent fluctuations in blood concentration levels. This is considered to be a cause of late motor complications which are troubling clinical and treatment issues of the disease.
The transdermal system developed in Dr. Sintov's lab is based on a pharmaceutical formulation of self-assembled, nano-structured soft micelles (electronically charged particles formed by an aggregate of molecules) containing high-limit concentrations of L-DOPA. The ongoing research will include physical, chemical and pharmacokinetic evaluations of the novel system.
The Bachmann-Strauss Dystonia & Parkinson Foundation, based in New York City, is a nonprofit organization whose work is made possible through the generosity of individuals, foundations and corporations. The Foundation was started to encourage new research and scientists in the fields of dystonia and Parkinson's disease.
American Associates, Ben-Gurion University of the Negev plays a vital role in sustaining David Ben-Gurion's vision, creating a world-class institution of education and research in the Israeli desert, nurturing the Negev community and sharing the University's expertise locally and around the globe. With some 20,000 students on campuses in Beer-Sheva, Sede Boqer and Eilat in Israel’s southern desert, BGU is a university with a conscience, where the highest academic standards are integrated with community involvement, committed to sustainable development of the Negev.
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